The peel of Musa paradisiaca as substitute for normal saline and sofratulle in the management
Musa paradisiaca (plantain) is widely cultivated for nutritional purposes with many health values being attributed to it. Its peel constitutes a significant proportion and usually dispose off as biological waste though it may be fed to ruminants. The probable roles of its peel in both powdery and ethanolic extracts in wound healing were investigated. The excisional wounds of thirty six adult male wistar rats in six equal groups were dressed with normal saline (NS), sofratulle (SF), ripe peel powder (RPP), unripe peel powder (UPP), ripe peel ethanolic extract (RPE) and unripe peel ethanolic extract (UPE) daily till healed. Mean wound contraction rates were determined from wound sizes every three days. Granulation tissue taken from an animal in each group every three days and together with end scar tissues were processed for histological analyses. The mean wound contraction rate on day 3 for the UPP group was significantly higher that of the RPP group. Also on day 3, that of the UPE was similarly significantly higher than that RPE. Although, the mean wound contraction rates of the control (NS and SF) were significantly higher than those of the peel groups on days 3,6 and 9, by day 12, the differences became insignificant. Histology of the granulation and scar tissues of both control and experimental showed similar features consistent with wound healing. Thus the powder and ethanolic extracts of ripe and unripe peel of M. paradisiaca accelerated healing of excisional wounds of wistar rats.
Arabloo J., S. Grey , M. Mobinizadeh, A. Olyaeemanesh , P. Hamouzadeh P, Khamisabadi K. Safety, effectiveness and economic aspects of maggot debridement therapy for wound healing. Med J Islam Repub Iran. 2016; 30: 319.
Dash, G.K., and P.N. Murthy.2011. Evaluation of Argemone Mexicana Linn. leaves for wound healing activity. J Nat Prod Plant Resour.1(1): 46-56.
Dei H. K., and Rose S. P., Mackenzie A. M. 2007. Shea nut (Vitellariaparadoxa) meal as a feed ingredient for poultry. Poultry Science, 63: 611-624
Emaga, T.H., R.H. Andrianaivo, B. Wathelet, J.T. Tchango, and M. Paquot .2007. Effects of the stage of maturation and varieties on the chemical composition of banana and plantain peels. Food Chemistry. 103: 590– 600.
Eun-Hye, L., Y. Hye-Jung, H. Mi-Sun, and B. Dong-Ho.2010. Development of banana peel jelly and its antioxidant and textural properties. Food Science Biotechnology. 19: 449-455.
http: // medbroadcast.com/drug/getdrug/sofra-tulle
.https :// woundcareadvisor.com/wp-content/uploads/2017/05/Angelini_BioPad_eBook.pdf
Humzah, M.D., J. Marshall ,and N.M. Breach. 1996. Eusol: the plastic surgeon's choice? J R Coll Surg Edinb. 41(4):269-270
Ighodaro, O.M. 2012. Evaluation study on Nigerian species of Musa paradisiaca Peels: Phytochemical screening, proximate analysis, Mineral Composition and Antimicrobial Activities. 4(8):17-20.
Jull, A.B., A. Rodgers, and N. Walker. 2008. Honey as a topical treatment for wounds. Cochrane Database of Systematic Reviews, Issue 4.Art. No.: CD005083. DOI: 10.1002/14651858.CD005083.pub2.
Junqueira, L.C., and J. Carneiro 2005. Basic Histology. New York: McGraw-Hill, New York. 93 pp
.Ketiku A.O. 1973. Chemical composition of unripe (green) and ripe plantain (Musa Paradisiaca). Journal of the Science of Food and Agriculture. 24(6): 703 – 707.
Marineau, M.L., M.T. Herrington, K.M. Swenor , and L.J. Eron. 2011. Maggot debridement therapy in the treatment of complex diabetic wounds. Hawaii Med J. 70(6):121-124.
Savithramma , N., M.L.Rao, and G. Bhum .2011. Phytochemical screening of Thespesia populnea (L.) Soland and Tridax procumbens L. J Chem Pharm Res. 3(5):28-34
Sherman, R.A.2009. Maggot therapy takes us back to the future of wound care: new and improved maggot therapy for the 21st century. J Diabetes Sci Technol. 3(2):336-344.
Shi E., and D. Shofler. 2014.Maggot debridement therapy: a systematic review. British Journal of Community Nursing .19: ( suppl 12) 6-13.
Soni, H., A.K. Singhai .2012. A recent update of botanicals for wound healing activity. International Research Journal of Pharmacy 3(7):1-7
Zamide, E.I., R.S. Ajani , and O.O. Oladapo.2015. Does lycoperscon esculentum (tomato) accelerate or retard wound healing in wistar rats? Anatomy Journal of Africa. 4(1): 522 – 527.